Associate Professor of Epidemiology, School of Public Health and Research Associate Professor, Survey Research Center, Institute for Social Research
Biography
Dr. Smith received her Ph.D. in Epidemiology, M.P.H. in Health Management and Policy, and M.A. in Statistics from the University of Michigan. She is currently a Research Assistant Professor in the Department of Epidemiology and Research Assistant Professor in the Survey Research Center at the Institute for Social Research and is affiliated with the Center for Integrated Approaches to Health Disparities (CIAHD), the Michigan Center on the Demography of Aging (MiCDA), and the Center for Midlife Science. Her research focuses on the “omic” epidemiology of chronic diseases and their risk factors. She is particularly interested in the impact of social and psychosocial factors on the genomic, epigenomic, and transcriptomic profiles underlying risk of dementia and cognitive decline.
Projects
Funded Research
- Alzheimer’s Disease Risk and Ethnic Factors: The Case of Arab Americans
- Characterizing disparities in late-onset Alzheimer’s disease risk through polygenic risk and epidemiologic factors in the Health and Retirement Survey
- Genomics for Social Scientists: 2022-2027
- Health and Retirement Study: Yrs 35-40
- Racial/Ethnic Disparities in ADRD Risk: The Impact of Social Relations
Publications
- Hao Mei, ..., Jennifer Ann Smith, Wei Zhao, et al.. 2024. Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance. Alzheimer's Research & Therapy 16(14)
- Suzuki, Ken, ..., Jennifer Ann Smith, et al.. 2024. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature 627(8003):347-357.
- Lauren A. Opsasnick, Wei Zhao, Lauren L. Schmitz, Scott M. Ratliff, Jessica Danielle Faul, Xiang Zhou, Belinda L. Needham, Jennifer Ann Smith. 2024. Epigenome-wide association study of long-term psychosocial stress in older adults. Epigenetics 19(1)
- Jessica I. Lundin, ..., Farah Ammous, Jennifer Ann Smith, Wei Zhao, et al.. 2024. Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations. Epigenetics 19(1)
- Lindsay A. Gallagher, Charles F. Schuler, Jonathan P. Troost, Ian F. Slack, Georgiana M. Sanders, James R. Baker, Jennifer Ann Smith, Kelly M. O'Shea. 2024. Racial and Socioeconomic Disparities Exist in Patients Pursuing Peanut Oral Immunotherapy. The Journal of Allergy and Clinical Immunology: In Practice 12(8):P2102-2108.
- Hrytsenko, Yana, ..., Jennifer Ann Smith, Wei Zhao, et al.. 2024. Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores. Scientific Reports 14(1):1-17.
- Janelle Vu Pugashetti, John S. Kim, Swaraj Bose, Ayodeji Adegunsoye, Angela L Linderholm, Ching-Hsien Chen, Mary E. Strek, Kevin R. Flaherty, Susan Murray, Chad A. Newton, Shehabaldin Alqalyoobi, Shwu-Fan Ma, Josyf C. Mychaleckyj, Russell P. Bowler, MeiLan K. Han, Jeffrey L. Curtis, Fernando J. Martinez, Jennifer Ann Smith, Imre Noth, Justin M. Oldham. 2024. Biological Age, Chronological Age and Survival in Pulmonary Fibrosis: A Causal Mediation Analysis. American Journal of Respiratory and Critical Care Medicine 210(5):639-647.
- Yi Zhe Wang, Wei Zhao, Priya Moorjani, Alden L. Gross, Xiang Zhou, Aparajit B. Dey, Jinkook Lee, Jennifer Ann Smith, Sharon L. R. Kardia. 2024. Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI‐DAD. Alzheimer's & Dementia 20(7):4854-4867.
- Stoldt, Meike, Farah Ammous, Lin,Lisha, Ratliff, Scott M, Erin Bakshis Ware, Jessica Danielle Faul, Wei Zhao, Kardia, Sharon L R, Jennifer Ann Smith. 2024. DNA Methylation at CRP-Associated CpG Sites May Mediate the Pathway between Educational Attainment and Cognition. The Journals of Gerontology: Series A 79(8):glae159.
- Stoldt, Meike, Farah Ammous, Lin, Lisha, Ratliff, Scott M, Erin Bakshis Ware, Jessica Danielle Faul, Wei Zhao, Kardia, Sharon L R, Jennifer Ann Smith. 2024. DNA Methylation at C-Reactive Protein-Associated CpG Sites May Mediate the Pathway Between Educational Attainment and Cognition. The Journals of Gerontology: Series A 79(8)
- Huffman, Jennifer E., ..., Jennifer Ann Smith, Wei Zhao, et al.. 2024. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Blood 144(21):2248-2265.
- Rocheleau, Ghislain, ..., Jennifer Ann Smith, et al.. 2024. Rare variant contribution to the heritability of coronary artery disease. Nature Communications 15(1):1-13.
- Jacquelyn Y. Taylor, Yunfeng Huang, Wei Zhao, Michelle L. Wright, Zeyuan Wang, Qin Hui, Stephanie Potts-Thompson, Veronica Barcelona, Laura Prescott, Yutong Yao, Cindy Crusto, Sharon L. R. Kardia, Jennifer Ann Smith, Yan V. Sun. 2023. Epigenome-wide association study of BMI in Black populations from InterGEN and GENOA. Obesity 31(1):243-255.
- Jinkook Lee, ..., Jennifer Ann Smith, Wei Zhao, Kenneth M Langa, et al.. 2023. Deep phenotyping and genomic data from a nationally representative study on dementia in India. Scientific Data 10:45.
- Chen, Fang, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2023. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nature Genetics 55:291-300.
- Julie Hahn, ..., Jennifer Ann Smith, Wei Zhao, et al.. 2023. DNA methylation analysis identifies novel genetic loci associated with circulating fibrinogen levels in blood. Journal of Thrombosis and Haemostasis
- Wei Zhao, Jennifer Ann Smith, Wang, Yi Zhe, Chintalapati, Manjusha, Ammous, Farah, Yu, Miao, Moorjani, Priya, Ganna, Andrea, Gross, Alden, Dey, Sharmistha, Benerjee, Joyita, Chatterjee, Prasun, Dey, Aparajit B, Lee, Jinkook, Kardia, Sharon L R. 2023. Polygenic risk scores for Alzheimer’s disease and general cognitive function are associated with measures of cognition in older South Asians from LASI-DAD. The Journals of Gerontology: Series A 78(5):743-752.
- Junyu Chen, Qin Hui, Zeyuan Wang, Francis P. Wilson, Kaku So-Armah, Matthew S. Freiberg, Amy C. Justice, Ke Xu, Wei Zhao, Farah Ammous, Jennifer Ann Smith, Sharon L. R Kardia, Marta Gwinn, Vincent C. Marconi, Yan V. Sun. 2023. Epigenome-wide meta-analysis reveals differential DNA methylation associated with estimated glomerular filtration rate among African American men with HIV. Kidney International Reports 8(5):1076-1086.
- Yuankai Zhang, ..., Wei Zhao, Jennifer Ann Smith, et al.. 2023. Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts. Neurology 100(18):e1930-e1943.
- Shang, Lulu, Wei Zhao, Wang, Yi Zhe, Li, Zheng, Choi, Jerome J., Kho, Minjung, Mosley, Thomas H., Kardia, Sharon L. R., Jennifer Ann Smith, Zhou, Xiang. 2023. meQTL mapping in the GENOA study reveals genetic determinants of DNA methylation in African Americans. Nature Communications 14(1):1-16.
- Leis, Aleda M., Mathis, Michael R., Kheterpal, Sachin, Zawistowski, Matthew, Mukherjee, Bhramar, Pace, Nathan, O'Reilly-Shah, Vikas N., Jennifer Ann Smith, Karvonen-Gutierrez, Carrie A.. 2023. Cardiometabolic disease and obesity patterns differentially predict acute kidney injury after total joint replacement: a retrospective analysis. British Journal of Anaesthesia 131(1):37-46.
- Nuzulul Kurniansyah, ..., Jennifer Ann Smith, et al.. 2023. Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups. Nature Communications 14:3202.
- Kira S Birditt, Angela Elizabeth Turkelson, Polenick, Courtney A, Cranford, James A, Jennifer Ann Smith, Erin Bakshis Ware, Blow, Frederic C. 2023. Alcohol Use and Mortality among Older Couples in the United States: Evidence of Individual and Partner Effects. The Gerontologist
- Iain Mathieson, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2023. Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. Nature Human Behaviour 7(5):790-801.
- Huichun Xu, ..., Wei Zhao, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, et al.. 2023. Exome Array Analysis of 9721 Ischemic Stroke Cases from the SiGN Consortium. Genes 14(1):61.
- Yordi J. van de Vegte, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2023. Genetic insights into resting heart rate and its role in cardiovascular disease. Nature Communications 14(1):1-21.
- Schmitz, Lauren L, Duffie, Elizabeth, Wei Zhao, Ratliff, Scott M, Ding, Jingzhong, Liu, Yongmei, Merkin, Sharon Stein, Jennifer Ann Smith, Seeman, Teresa. 2023. Early-Life Adversity Associations With Later Life Epigenetic Aging Profiles in the Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology 192(12):1991–2005.
- Maxwell Salvatore, Dylan Clark-Boucher, Lars G Fritsche, Jacob Ortlieb, Janet Houghtby, Anisa Driscoll, Bryanne Caldwell-Larkins, Jennifer Ann Smith, Chad M Brummett, Sachin Kheterpal, Lynda Lisabeth, Bhramar Mukherjee. 2023. Cohort profile: Epidemiologic Questionnaire (EPI-Q) – a scalable, app-based health survey linked to electronic health record and genotype data. Epidemiology and Health :e2023074.
- Gao, Tao, Zheng, Yinan, Joyce, Brian T, Kho, Minjung, Terry, James G, Wang, Jun, Nannini, Drew, Carr, John Jeffrey, Nair, Sangeeta, Zhang, Kai, Wei Zhao, Jacobs, David R, Schreiner, Pamela J, Greenland, Philip, Lloyd-Jones, Donald, Jennifer Ann Smith, Hou, Lifang. 2023. Epigenetic Aging is Associated with Measures of Midlife Muscle Volume and Attenuation in CARDIA Study. The Journals of Gerontology: Series A
- Natalie R. Hasbani, ..., Jennifer Ann Smith, et al.. 2023. Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis. Circulation: Genomic and Precision Medicine
- Dylan Clark-Boucher, Xiang Zhou, Jiacong Du, Yongmei Liu, Belinda L Needham, Jennifer Ann Smith, Bhramar Mukherjee. 2023. Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons. PLoS genetics 19(11)
- de Vries, Paul S., ..., Jennifer Ann Smith, Wei Zhao, et al.. 2023. Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification. Nature Cardiovascular Research :1-14.
- Schmitz, Lauren L, Duffie, Elizabeth, Wei Zhao, Ratliff, Scott M, Ding, Jingzhong, Liu, Yongmei, Merkin, Sharon Stein, Jennifer Ann Smith, Seeman, Teresa. 2023. Associations of Early-Life Adversity With Later-Life Epigenetic Aging Profiles in the Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology 192(12):1991-2005.
- Armstrong, Nicole D., ..., Wei Zhao, Jennifer Ann Smith, et al.. 2023. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program. Frontiers in Genetics 14:1278215.
- Taub, Margaret A., ..., Jennifer Ann Smith, et al.. 2022. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genomics 2(1):100084-undefined.
- Ammous, Farah, Zhao, Wei, Lin, Lisha, Ratliff, Scott M., Mosley, Thomas H., Bielak, Lawrence F., Zhou, Xiang, Peyser, Patricia A., Kardia, Sharon L. R., Jennifer Ann Smith. 2022. Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA). Clinical Epigenetics 14(1):10.
- Daniel DiCorpo, ..., Jennifer Ann Smith, et al.. 2022. Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 individuals Across 13 Cohorts. Diabetes care 45(3):674-683.
- Lawrence F Bielak, Patricia A Peyser, Jennifer Ann Smith, Wei Zhao, Edward A Ruiz-Narvaez, Sharon L R Kardia, Harlow,Sioban D. 2022. Multivariate, region-based genetic analyses of facets of reproductive aging in White and Black women. Molecular genetics & genomic medicine 10(4):e1896.
- Fiorito, Giovanni, ..., Jennifer Ann Smith, et al.. 2022. The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis. The Journals of Gerontology: Series A
- He, Karen Y., ..., Jennifer Ann Smith, et al.. 2022. Rare coding variants in RCN3 are associated with blood pressure. BMC Genomics 23:148.
- Zheng Li, Wei Zhao, Lulu Shang, Thomas H. Mosley, Sharon L.R. Kardia, Jennifer Ann Smith, Xiang Zhou. 2022. METRO: Multi-ancestry transcriptome-wide association studies for powerful gene-trait association detection. The American Journal of Human Genetics
- Tetsushi Nakao, ..., Jennifer Ann Smith, et al.. 2022. Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential. Science Advances 8(14)
- Mishra, Aniket, ..., Jennifer Ann Smith, et al.. 2022. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain
- Howe, Laurence J., ..., Jennifer Ann Smith, et al.. 2022. Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nature Genetics
- Amir Carter, Cristina Bares, Lisha Lin, Beth Glover Reed, Marjorie Bowden, Robert A. Zucker, Wei Zhao, Jennifer Ann Smith, Jill B. Becker. 2022. Sex-specific and Generational Effects of Alcohol and Tobacco Use on Epigenetic Age Acceleration in the Michigan Longitudinal Study. Drug and Alcohol Dependence Reports 4:100077.
- Dylan Clark-Boucher, Jonathan Boss, Maxwell Salvatore, Jennifer Ann Smith, Lars G. Fritsche, Bhramar Mukherjee. 2022. Assessing the added value of linking electronic health records to improve the prediction of self-reported COVID-19 testing and diagnosis. PLOS ONE 17(7):e0269017.
- Jang, Seon-Kyeong, ..., Jennifer Ann Smith, et al.. 2022. Rare genetic variants explain missing heritability in smoking. Nature Human Behaviour 6:1577-1586.
- Lahti, Jari, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2022. Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. Molecular Psychiatry [Epub] [Full Text]
- Lauren L. Schmitz, Wei Zhao, Scott M. Ratliff, Julia Goodwin, Jiacheng Miao, Qiongshi Lu, Xiuqing Guo, Kent D. Taylor, Jingzhong Ding, Yongmei Liu, Morgan Levine, Jennifer Ann Smith. 2022. The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study. Epigenetics 17(6)
- Yi Zhe Wang, Wei Zhao, Farah Ammous, Yanyi Song, Jiacong Du, Lulu Shang, Scott M. Ratliff, Kari Moore, Kristen M. Kelly, Belinda L. Needham, Ana V. Diez Roux, Yongmei Liu, Kenneth R. Butler, Sharon L. R. Kardia, Bhramar Mukherjee, Xiang Zhou, Jennifer Ann Smith. 2022. DNA Methylation Mediates the Association Between Individual and Neighborhood Social Disadvantage and Cardiovascular Risk Factors. Frontiers in Cardiovascular Medicine 9:848768.
- Thomas Jaworek, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, et al.. 2022. Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke. Neurology 99(16):e1738-e1754.
- Jones, Alana C., Patki, Amit, Claas, Steven A., Tiwari, Hemant K., Chaudhary, Ninad S., Absher, Devin M., Lange, Leslie A., Lange, Ethan M., Zhao, Wei, Ratliff, Scott M., Kardia, Sharon L. R., Jennifer Ann Smith, Irvin, Marguerite R., Arnett, Donna K.. 2022. Differentially Methylated DNA Regions and Left Ventricular Hypertrophy in African Americans: A HyperGEN Study. Genes 13(10):1700.
- Zhangchen Zhao, Lars G. Fritsche, Jennifer Ann Smith, Bhramar Mukherjee, Seunggeun Lee. 2022. The construction of cross-population polygenic risk scores using transfer learning. The American Journal of Human Genetics 109(11):1998-2008.
- Zhang, Xinman, Ammous, Farah, Lin, Lisha, Ratliff, Scott M., Erin Bakshis Ware, Jessica Danielle Faul, Wei Zhao, Kardia, Sharon L. R., Jennifer Ann Smith. 2022. The Interplay of Epigenetic, Genetic, and Traditional Risk Factors on Blood Pressure: Findings from the Health and Retirement Study. Genes 13(11):1959.
- Chaar, Dima L., Nguyen, Kim, Wang, Yi-Zhe, Ratliff, Scott M., Mosley, Thomas H., Kardia, Sharon L. R., Jennifer Ann Smith, Wei Zhao. 2022. SNP-by-CpG Site Interactions in ABCA7 Are Associated with Cognition in Older African Americans. Genes 13(11):2150.
- Pan, Yang, ..., Jennifer Ann Smith, et al.. 2022. Whole-Exome Sequencing Study Identifies Four Novel Gene Loci Associated with Diabetic Kidney Disease. Human Molecular Genetics 36(6):1048-1060.
- Gretchen R. B. Saunders, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2022. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 612:720-724.
- Li, Xihao, ..., Jennifer Ann Smith, Wei Zhao, et al.. 2022. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nature Genetics 55:154-164.
- Tanika N. Kelly, ..., Jennifer Ann Smith, et al.. 2022. Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension. Hypertension 79(8):1656–1667.
- Howe, Laurence J., ..., Jennifer Ann Smith, et al.. 2022. Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nature Genetics 54(5):581-592.
- Lindsay Fernández-Rhodes, ..., Jennifer Ann Smith, et al. 2022. Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits — The Hispanic/Latino Anthropometry Consortium. Human Genetics and Genomics Advances 3(2):100099.
- Stavroula Kanoni, ..., Jessica Danielle Faul, Wei Zhao, David R Weir, Jennifer Ann Smith, et al.. 2022. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Genome Biology 23(1):1-42.
- Loïc Yengo, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2022. A saturated map of common genetic variants associated with human height. Nature 610(7933):704-712.
- Jennifer Ann Smith, Minjung Kho, Wei Zhao, Miao Yu, Colter Mitchell, Jessica Danielle Faul. 2021. Genetic effects and gene-by-education interactions on episodic memory performance and decline in an aging population. Social Science & Medicine 271:112039.
- Farah Ammous, Wei Zhao, Scott M. Ratliff, Minjung Kho, Lulu Shang, Alana C. Jones, Ninad S. Chaudhary, Hemant K. Tiwari, Marguerite R. Irvin, Donna K. Arnett, Thomas H. Mosley, Lawrence F. Bielak, Sharon L. R. Kardia, Xiang Zhou, Jennifer Ann Smith. 2021. Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans. Epigenetics 16(8):862-875.
- Wei Zhao, Jennifer Ann Smith, Lawrence F. Bielak, Edward A. Ruiz-Narvaez, Miao Yu, Michelle M. Hood, Patricia A. Peyser, Sharon L. R. Kardia, Sioban D. Harlow. 2021. Associations between polygenic risk score for age at menarche and menopause, reproductive timing, and serum hormone levels in multiple race/ethnic groups. Menopause 28(7):819-828.
- Farah Ammous, Wei Zhao, Scott M. Ratliff, Thomas H. Mosley, Lawrence F. Bielak, Xiang Zhou, Patricia A. Peyser, Sharon L. R. Kardia, Jennifer Ann Smith. 2021. Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans. Clinical Epigenetics 13(1):55.
- Kelly M. Bakulski, Vadari,Harita Shree, Jessica Danielle Faul, Steven G Heeringa, Sharon L. R. Kardia, Kenneth M Langa, Jennifer Ann Smith, Jennifer J. Manly, Colter Mitchell, Kelly S. Benke, Erin Bakshis Ware. 2021. Cumulative Genetic Risk and APOE ε4 Are Independently Associated With Dementia Status in a Multiethnic, Population-Based Cohort. Neurology Genetics 7(2):e576.
- Kristen Kelly, Jennifer Ann Smith, Briana Mezuk. 2021. Depression and interleukin-6 signaling: A Mendelian Randomization Study. Brain, Behavior, and Immunity 95:106-114.
- Zhao, Wei, Jennifer Ann Smith, Yu, Miao, Crandall, Carolyn J., Thurston, Rebecca C., Hood, Michelle M., Ruiz-Narvaez, Edward, Peyser, Patricia A., Kardia, Sharon L.R., Harlow, Sioban D.. 2021. Genetic variants predictive of reproductive aging are associated with vasomotor symptoms in a multiracial/ethnic cohort. Menopause 28(8):883-892.
- Minjung Kho, Yi Zhe Wang, Dima Chaar, Wei Zhao, Scott M. Ratliff, Thomas H. Mosley, Patricia A. Peyser, Sharon L.R. Kardia, Jennifer Ann Smith. 2021. Accelerated DNA methylation age and medication use among African Americans. Aging 13(11):14604-14629.
- Wang, Penglong, Castellani, Christina A, Yao, Jie, Huan, Tianxiao, Bielak, Lawrence F, Zhao, Wei, Haessler, Jeffrey, Roby, Joehanes, Sun, Xianbang, Guo, Xiuqing, Longchamps, Ryan J, Manson, JoAnn E, Grove, Megan L, Bressler, Jan, Taylor, Kent D, Lappalainen, Tuuli, Kasela, Silva, Van Den Berg, David J, Hou, Lifang, Reiner, Alexander, Liu, Yongmei, Boerwinkle, Eric, Jennifer Ann Smith, Peyser, Patricia A, Fornage, Myriam, Rich, Stephen S, Rotter, Jerome I, Kooperberg, Charles, Arking, Dan E, Levy, Daniel, Liu, Chunyu, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. 2021. Epigenome-wide association study of mitochondrial genome copy number. Human Molecular Genetics 31(2):309-319.
- Jessica Danielle Faul, Kho, Minjung, Zhao, Wei, Rumfelt, Kalee E, Yu, Miao, Colter Mitchell, Jennifer Ann Smith. 2021. Trans-ethnic Meta-analysis of Interactions between Genetics and Early Life Socioeconomic Context on Memory Performance and Decline in Older Americans. The Journals of Gerontology: Series A
- Xue Liu, Ryan J. Longchamps, Kerri L. Wiggins, Laura M. Raffield, Lawrence F. Bielak, Wei Zhao, Achilleas Pitsillides, Thomas W. Blackwell, Jie Yao, Xiuqing Guo, Nuzulul Kurniansyah, Bharat Thyagarajan, Nathan Pankratz, Stephen S. Rich, Kent D. Taylor, Patricia A. Peyser, Susan R. Heckbert, Sudha Seshadri, L. Adrienne Cupples, Eric Boerwinkle, Megan L. Grove, Nicholas B. Larson, Jennifer Ann Smith, Ramachandran S. Vasan, Tamar Sofer, Annette L. Fitzpatrick, Myriam Fornage, Jun Ding, Adolfo Correa, Goncalo Abecasis, Bruce M. Psaty, James G. Wilson, Daniel Levy, Jerome I. Rotter, Joshua C. Bis, TOPMed mtDNA Working Group in NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Claudia L. Satizaba, Dan E. Arking, Chunyu Liu. 2021. Association of mitochondrial DNA copy number with cardiometabolic diseases. Cell Genomics 1(1):100006.
- Schlosser, Pascal, ..., Jennifer Ann Smith, et al.. 2021. Meta-analyses identify DNA methylation associated with kidney function and damage. Nature Communications 12:7174.
- Tin, Adrienne, ..., Jennifer Ann Smith, et al.. 2021. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nature Communications 12:7173.
- Yanyi Song, Xiang Zhou, Jian Kang, Max T. Aung, Min Zhang, Wei Zhao, Belinda L. Needham, Sharon L. R. Kardia, Yongmei Liu, John D. Meeker, Jennifer Ann Smith, Bhramar Mukherjee. 2021. Bayesian hierarchical models for high-dimensional mediation analysis with coordinated selection of correlated mediators. Statistics in Medicine 40(27):6038-6056.
- Stilp, Adrienne M, ..., Jennifer Ann Smith, et al.. 2021. A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program. American Journal of Epidemiology 190(10):1977-1992.
- Ruth, Katherine S., ..., Jennifer Ann Smith, et al.. 2021. Genetic Insights Into Biological Mechanisms Governing Human Ovarian Ageing. Obstetrical & Gynecological Survey 76(11):678-679.
- Daokun Sun, ..., Jessica Danielle Faul, Jennifer Ann Smith, Erin Bakshis Ware, David R Weir, et al.. 2021. Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits. Human Genetics and Genomics Advances 2(1):100013.
- Bridget M. Lin, ..., Jennifer Ann Smith, et al.. 2021. Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. EBioMedicine 63:103157.
- Christiansen, C., Castillo-Fernandez, J. E., Domingo-Relloso, A., Zhao, W., El-Sayed Moustafa, J. S., Tsai, P.-C., Maddock, J., Haack, K., Cole, S. A., Kardia, S. L. R., Molokhia, M., Suderman, M., Power, C., Relton, C., Wong, A., Kuh, D., Goodman, A., Small, K. S., Jennifer Ann Smith, Tellez-Plaza, M., Navas-Acien, A., Ploubidis, G. B., Hardy, R., Bell, J. T.. 2021. Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects. Clinical Epigenetics 13
- Taliun, Daniel, ..., Jennifer Ann Smith, et al.. 2021. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature 590(7845):290-299.
- Katherine S. Ruth, ..., Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Wei Zhao, et al.. 2021. Genetic insights into biological mechanisms governing human ovarian ageing. Nature 596(7872):393-397.
- Mariaelisa Graff, ..., Jessica Danielle Faul, Erin Bakshis Ware, David R Weir, Jennifer Ann Smith, Wei Zhao, et al.. 2021. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. American journal of human genetics 108(4):564-582.
- Vladimir B. Seplyarskiy, ..., Jennifer Ann Smith, et al.. 2021. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science 373(6558):1030-1035.
- Bressler, Jan, ..., Jennifer Ann Smith, Wei Zhao, Erin Bakshis Ware, et al.. 2021. Association of low-frequency and rare coding variants with information processing speed. Translational Psychiatry 11:613.
- Wen, Jia, ..., Jennifer Ann Smith, Wei Zhao, et al.. 2021. Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations. Genes 12(7):1049.
- Jennifer Ann Smith, Assari, Shervin , Javanbakht, Arash , Saqib, Mohammed , Helmi, Hamid , Bazargan, Mohsen . 2020. Neuroticism polygenic risk score is associated with 20-year average depressive symptoms for Whites but not Blacks. Journal of Medical Research and Innovation 14(1):e000183.
- Jennifer Ann Smith, Zhao, Wei, Kardia, Sharon R., Shang, Lulu , Kho, Minjung , Turner, Stephen T, Mosley, Thomas H, Zhou, Xiang . 2020. Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA. The American Journal of Human Genetics 106(4):496-512.
- Kristen M. Brown, Ana V. Diez-Roux, Jennifer Ann Smith, Needham,Belinda L, Bhramar Mukherjee, Erin Bakshis Ware, Yongmei Liu, Steven W. Cole, Teresa E. Seeman, Sharon L. R. Kardia. 2020. Social regulation of inflammation related gene expression in the multi-ethnic study of atherosclerosis. Psychoneuroendocrinology 117:104654.
- Minjung Kho, Wei Zhao, Scott M. Ratliff, Farah Ammous, Thomas H. Mosley, Lulu Shang, Sharon L. R. Kardia, Xiang Zhou, Jennifer Ann Smith. 2020. Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study. BMC Medical Genomics 13(1):131.
- Minjung Kho, Jennifer Ann Smith, ..., Erin Bakshis Ware, et al.. 2020. Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies Suggestive Loci for Sodium Intake, Potassium Intake, and Their Ratio Measured from 24-Hour or Half-Day Urine Samples. The Journal of Nutrition 150(10):2635-2645.
- Jennifer Ann Smith, Wei Zhao, Miao Yu, Kalee E. Rumfelt, Priya Moorjani, Andrea Ganna, Aparajit B. Dey, Jinkook Lee, Sharon L. R. Kardia. 2020. Association Between Episodic Memory and Genetic Risk Factors for Alzheimerâs Disease in South Asians from the Longitudinal Aging Study in IndiaâDiagnostic Assessment of Dementia (LASI-DAD). Journal of the American Geriatrics Society 68(S3):S45-S53.
- Xueqiu Jian, Tamar Sofer, Wassim Tarraf, Jan Bressler, Jessica Danielle Faul, Wei Zhao, Scott M. Ratliff, Melissa Lamar, Lenore J. Launer, Cathy C. Laurie, Neil Schneiderman, David R Weir, Clinton B. Wright, Kristine Yaffe, Donglin Zeng, Charles DeCarli, Thomas H. Mosley, Jennifer Ann Smith, Hector M. González, Myriam Fornage. 2020. Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos. Translational Psychiatry 10(1):1-13.
- Muralidharan Sargurupremraj, Hideaki Suzuki, Xueqiu Jian, Chloé Sarnowski, Tavia E. Evans, Joshua C. Bis, Gudny Eiriksdottir, Saori Sakaue, Natalie Terzikhan, Mohamad Habes, Wei Zhao, Nicola J. Armstrong, Edith Hofer, Lisa R. Yanek, Saskia P. Hagenaars, Rajan B. Kumar, Erik B. Akker, Rebekah E. McWhirter, Stella Trompet, Aniket Mishra, Yasaman Saba, Claudia L. Satizabal, Gregory Beaudet, Laurent Petit, Ami Tsuchida, Laure Zago, Sabrina Schilling, Sigurdur Sigurdsson, Rebecca F. Gottesman, Cora E. Lewis, Neelum T. Aggarwal, Oscar L. Lopez, Jennifer Ann Smith, Maria C. Valdés Hernández, Jeroen Grond, Margaret J. Wright, Maria J. Knol, Marcus Dörr, Russell J. Thomson, Constance Bordes, Quentin Le Grand, Marie-Gabrielle Duperron, Albert V. Smith, David S. Knopman, Pamela J. Schreiner, Denis A. Evans, Jerome I. Rotter, Alexa S. Beiser, Susana Muñoz Maniega, Marian Beekman, Julian Trollor, David J. Stott, Meike W. Vernooij, Katharina Wittfeld, Wiro J. Niessen, Aicha Soumaré, Eric Boerwinkle, Stephen Sidney, Stephen T. Turner, Gail Davies, Anbupalam Thalamuthu, Uwe Völker, Mark A. Buchem, R. Nick Bryan, Josée Dupuis, Mark E. Bastin, David Ames, Alexander Teumer, Philippe Amouyel, John B. Kwok, Robin Bülow, Ian J. Deary, Peter R. Schofield, Henry Brodaty, Jiyang Jiang, Yasuharu Tabara, Kazuya Setoh, Susumu Miyamoto, Kazumichi Yoshida, Manabu Nagata, Yoichiro Kamatani, Fumihiko Matsuda, Bruce M. Psaty, David A. Bennett, Philip L. De Jager, Thomas H. Mosley, Perminder S. Sachdev, Reinhold Schmidt, Helen R. Warren, Evangelos Evangelou, David-Alexandre Trégouët, Mohammad A. Ikram, Wei Wen, Charles DeCarli, Velandai K. Srikanth, J. Wouter Jukema, Eline P. Slagboom, Sharon L. R. Kardia, Yukinori Okada, Bernard Mazoyer, Joanna M. Wardlaw, Paul A. Nyquist, Karen A. Mather, Hans J. Grabe, Helena Schmidt, Cornelia M. Van Duijn, Vilmundur Gudnason, William T. Longstreth, Lenore J. Launer, Mark Lathrop, Sudha Seshadri, Christophe Tzourio, Hieab H. Adams, Paul M. Matthews, Myriam Fornage, Stéphanie Debette. 2020. Cerebral small vessel disease genomics and its implications across the lifespan. Nature Communications 11(1):6285.
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- Zuyun Liu, Diana Leung, Kyra Thrush, Wei Zhao, Scott Ratliff, Toshiko Tanaka, Lauren L. Schmitz, Jennifer Ann Smith, Luigi Ferrucci, Morgan E. Levine. 2020. Underlying features of epigenetic aging clocks in vivo and in vitro. Aging Cell 19(10):e13229.
- Lulu Shang, Jennifer Ann Smith, Xiang Zhou. 2020. Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies. PLOS Genetics 16(4):e1008734.
- Shervin Assari, Arash Javanbakht, Mohammed Saqib, Hamid Helmi, Mohsen Bazargan, Jennifer Ann Smith. 2020. Neuroticism polygenic risk score predicts 20-year burden of depressive symptoms for Whites but not Blacks. Journal of Medical Research and Innovation 4(1):e000183.
- Yanyi Song, Xiang Zhou, Min Zhang, Wei Zhao, Yongmei Liu, Sharon L. R. Kardia, Ana V. Diez Roux, Belinda L. Needham, Jennifer Ann Smith, Bhramar Mukherjee. 2020. Bayesian shrinkage estimation of high dimensional causal mediation effects in omics studies. Biometrics 76(3):700-710.
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- Jennifer Ann Smith, Kardia, Sharon R., Chen, Han , Huffman, Jennifer E, Brody, Jennifer A, Wang, Chaolong , Lee, Seunggeun , Li, Zilin , Gogarten, Stephanie M, Sofer, Tamar , Bielak, Lawrence F, Bis, Joshua C, Blangero, John , Bowler, Russell P, Cade, Brian E, Cho, Michael H, Correa, Adolfo , Curran, Joanne E, de Vries, Paul S, Glahn, David C, Guo, Xiuqing , Johnson, Andrew D, Kooperberg, Charles , Lewis, Joshua P, Liu, Xiaoming , Mathias, Rasika A, Mitchell, Braxton D, O'Connell, Jeffrey R, Peyser, Patricia A, Post, Wendy S, Reiner, Alex P, Rich, Stephen S, Rotter, Jerome I, Silverman, Edwin K, Vasan, Ramachandran S, Wilson, James G, Yanek, Lisa R, Redline, Susan , Smith, Nicholas L, Boerwinkle, Eric , Borecki, Ingrid B, Cupples, L Adrienne, Laurie, Cathy C, Morrison, Alanna C, Rice, Kenneth M, Lin, Xihong . 2019. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies. The American Journal of Human Genetics 104(2):260-274.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Kardia, Sharon R., de Vries, Paul S, Brown, Michael R, Bentley, Amy R, Sung, Yun J, Winkler, Thomas W, Ntalla, Ioanna , Schwander, Karen , Kraja, Aldi T, Guo, Xiuqing , Franceschini, Nora , Cheng, Ching-Yu , Sim, Xueling , Vojinovic, Dina , Huffman, Jennifer E, Musani, Solomon K. 2019. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology 188(6):1033-1054.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Taylor, Jacquelyn Y, Wright, Michelle L. 2019. Using Genetic Burden Scores for Gene-by-Methylation Interaction Analysis on Metabolic Syndrome in African Americans. Biological Research For Nursing 21(3):279-285.
- Jennifer Ann Smith, Kardia, Sharon R., Ma, Jiantao , Nano, Jana , Ding, Jingzhong , Zheng, Yinan , Hennein, Rachel , Liu, Chunyu , Speliotes, Elizabeth K, Huan, Tianxiao , Song, Ci , Mendelson, Michael M, Joehanes, Roby , Long, Michelle T, Liang, Liming , Reynolds, Lindsay , Ghanbari, Mohsen , Muka, Taulant , Meurs, Joyce van, Alferink, Louise J. M., Franco, Oscar H, Dehghan, Abbas , Ratliff, Scott , Bielak, Lawrence , Peyser, Patricia A, Ning, Hongyan , VanWagner, Lisa B, Lloyd-Jones, Donald M, Carr, John Jeffrey, Greenland, Philip , Lichtenstein, Alice H, Hu, Frank B, Liu, Yongmei , Hou, Lifang , Murad, Sarwa Darwish, Levy, Daniel . 2019. A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Non-Alcoholic Fatty Liver Disease. Diabetes 68(5):1073-1083.
- Jennifer Ann Smith, Kardia, Sharon R., Schlicht, Kristina , Nyczka, Piotr , Caliebe, Amke , Freitag-Wolf, Sandra , Claringbould, Annique , Franke, Lude , Võsa, Urmo , Gieger, Christian , Peters, Annette , Prokisch, Holger , Strauch, Konstantin , Baurecht, Hansjörg , Weidinger, Stephan , Rosenstiel, Philip , Hütt, Marc-Thorsten , Knecht, Carolin , Szymczak, Silke , Krawczak, Michael . 2019. The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. Human Genetics 138(4):375-388.
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- Jennifer Ann Smith, Kardia, Sharon R., He, Karen Y, Li, Xiaoyin , Kelly, Tanika N, Liang, Jingjing , Cade, Brian E, Assimes, Themistocles L, Becker, Lewis C, Beitelshees, Amber L, Bress, Adam P, Chang, Yen-Pei Christy, Chen, Yii-Der Ida, de Vries, Paul S, Fox, Ervin R, Franceschini, Nora , Furniss, Anna , Gao, Yan , Guo, Xiuqing , Haessler, Jeffrey . 2019. Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data. Human Genetics 138(2):199-210.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Kardia, Sharon R., Sung, Yun Ju, de las Fuentes, Lisa , Winkler, Thomas W, Chasman, Daniel I, Bentley, Amy R, Kraja, Aldi T, Ntalla, Ioanna , Warren, Helen R, Guo, Xiuqing , Schwander, Karen , Manning, Alisa K, Brown, Michael R, Aschard, Hugues , Feitosa, Mary F, Franceschini, Nora . 2019. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics 28(15):2615-2633.
- Jennifer Ann Smith, Erin Bakshis Ware, Needham, Belinda L., Kardia, Sharon R., Brown, Kristen M, Diez-Roux, Ana V, Mukherjee, Bhramar , Liu, Yongmei , Cole, Steven W, Seeman, Teresa E. 2019. Expression of socially sensitive genes: The multi-ethnic study of atherosclerosis. PLOS ONE 14(4):e0214061.
- Jennifer Ann Smith, Liu, Jiaxuan , Ammous, Farah , Turner, Stephen T, Mosley, Thomas H, Zhou, Xiang . 2019. Longitudinal analysis of epigenome-wide DNA methylation reveals novel smoking-related loci in African Americans. Epigenetics 14(2):171-184.
- Jennifer Ann Smith, Kardia, Sharon R., Barcelona, Veronica , Huang, Yunfeng , Brown, Kristen , Liu, Jiaxuan , Yu, Miao , Taylor, Jacquelyn Y, Sun, Yan V. 2019. Novel DNA methylation sites associated with cigarette smoking among African Americans. Epigenetics 14(4):383-391.
- Jennifer Ann Smith, Liu, Jun , Carnero-Montoro, Elena , Dongen, Jenny van, Lent, Samantha , Nedeljkovic, Ivana , Ligthart, Symen , Tsai, Pei-Chien , Martin, Tiphaine C, Mandaviya, Pooja R, Jansen, Rick , Peters, Marjolein J, Duijts, Liesbeth , Jaddoe, Vincent W. V., Tiemeier, Henning , Felix, Janine F, Willemsen, Gonneke , Geus, Eco J. C. de, Chu, Audrey Y, Levy, Daniel . 2019. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications 10(1):2581.
- Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Zhao, Wei, Kardia, Sharon R., Evangelou, Evangelos , Gao, He , Chu, Congying , Ntritsos, Georgios , Blakeley, Paul , Butts, Andrew R, Pazoki, Raha , Suzuki, Hideaki , Koskeridis, Fotios , Yiorkas, Andrianos M, Karaman, Ibrahim , Elliott, Joshua , Luo, Qiang , Aeschbacher, Stefanie , Bartz, Traci M. 2019. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour 3:950-961.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Kardia, Sharon R., Deelen, Joris , Evans, Daniel S, Arking, Dan E, Tesi, Niccolò , Nygaard, Marianne , Liu, Xiaomin , Wojczynski, Mary K, Biggs, Mary L, Spek, A van der, Atzmon, Gil , Sarnowski, Chloé , Smith, Albert V, Seppälä, Ilkka , Cordell, Heather J, Dose, Janina . 2019. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications 10:3669.
- Jennifer Ann Smith, Bakulski, Kelly Marie, Murphy, Susan A., Kardia, Sharon R., Sikdar, Sinjini , Joehanes, Roby , Joubert, Bonnie R, Xu, Cheng-Jian , Vives-Usano, Marta , Rezwan, Faisal I, Felix, Janine F, Ward, James M, Guan, Weihua , Richmond, Rebecca C, Brody, Jennifer A, Küpers, Leanne K, Baïz, Nour , Håberg, Siri E, Reese, Sarah E, Aslibekyan, Stella . 2019. Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics 11(13):1487-1500.
- Jennifer Ann Smith, Kardia, Sharon R., Zhao, Wei, Raisky, Jeremy , Ratliff, Scott M, Liu, Jiaxuan , Turner, Stephen T, Mosley, Thomas H. 2019. Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans. BMC Medical Genomics 12(1):141.
- Jennifer Ann Smith, Besser, Lilah , Galvin, James E, Rodriguez, Daniel , Seeman, Teresa , Kukull, Walter , Rapp, Stephen R. 2019. Associations between neighborhood built environment and cognition vary by apolipoprotein E genotype: Multi-Ethnic Study of Atherosclerosis. Health & Place 60:102188.
- Madeline H. Kowalski, ..., Jennifer Ann Smith. 2019. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. PLOS Genetics 15(12):e1008500.
- Jennifer Ann Smith, Raisky, Jeremy, Ratliff, Scott M., Liu, Jiaxuan, Kardia, Sharon L. R., Turner, Stephen T., Mosley, Thomas H., Zhao, Wei. 2019. Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans. BMC Medical Genomics 12:141.
- Erin Bakshis Ware, Jennifer Ann Smith, Wei Zhao, Ron T. Ganesvoort, Gary C. Curhan, Martin Pollak, David B. Mount, Stephen T. Turner, Guotao Chen, Ronak Jagdeep Shah, Sharon L.R. Kardia, John C. Lieske. 2019. Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Mayo Clinic Proceedings: Innovations, Quality & Outcomes 3(4):448-460.
- Zhao, Wei, Ammous, Farah, Ratliff, Scott, Liu, Jiaxuan, Yu, Miao, Mosley, Thomas H., Kardia, Sharon L. R., Jennifer Ann Smith. 2019. Education and Lifestyle Factors Are Associated with DNA Methylation Clocks in Older African Americans. International Journal of Environmental Research and Public Health 16(17):3141.
- Anh N. Do, Wei Zhao, Abigail S. Baldridge, Laura M. Raffield, Kerri L. Wiggins, Sanjiv J. Shah, Stella Aslibekyan, Hemant K. Tiwari, Nita Limdi, Degui Zhi, Colleen M. Sitlani, Kent D. Taylor, Bruce M. Psaty, Nona Sotoodehnia, Jennifer A. Brody, Laura J. Rasmussen-Torvik, Donald Lloyd-Jones, Leslie A. Lange, James G. Wilson, Jennifer Ann Smith, Sharon L. R. Kardia, Thomas H. Mosley, Ramachandran S. Vasan, Donna K. Arnett, Marguerite R. Irvin. 2019. Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans. Molecular Genetics & Genomic Medicine 7(10):e00788.
- Cavin K. Ward-Caviness, ..., Jennifer Ann Smith, et al.. 2019. Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease. PLOS ONE 14(5):e0216222.
- Amy R. Bentley, ..., Jessica Danielle Faul, Erin Bakshis Ware, David R Weir, Jennifer Ann Smith, Wei Zhao, et al.. 2019. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics 51(4):636-648.
- Jennifer Ann Smith, Sharma, M , Farquhar, C , Ying, R , Cherutich, P , Golden, M , Wamuti, B , Bukusi, D , Spiegel, H , Barnabas, R V. 2018. Assisted partner notification services are cost-effective for decreasing HIV burden in western Kenya: A mathematical modeling analysis. AIDS 32(2):233-241.
- Jennifer Ann Smith, Kardia, Sharon R., Marioni, Riccardo E, McRae, Allan F, Bressler, Jan , Colicino, Elena , Hannon, Eilis , Li, Shuo , Prada, Diddier , Trevisi, Letizia , Tsai, Pei-Chien , Vojinovic, Dina , Simino, Jeannette , Levy, Daniel , Liu, Chunyu , Mendelson, Michael , Satizabal, Claudia L, Yang, Qiong , Jhun, Min A, Bandinelli, Stefania , Ferrucci, Luigi , Hernandez, Dena G, Singleton, Andrew B, Harris, Sarah E, Starr, John M, Kiel, Douglas P, McLean, Robert R, Just, Allan C, Schwartz, Joel , Spiro, Avron , Vokonas, Pantel , Amin, Najaf , Ikram, M Arfan, Uitterlinden, Andre G, Meurs, Joyce B. J., Spector, Tim D, Steves, Claire , Baccarelli, Andrea A, Bell, Jordana T, Duijn, Cornelia M, Fornage, Myriam , Hsu, Yi-Hsiang , Mill, Jonathan , Mosley, Thomas H, Seshadri, Sudha , Deary, Ian J. 2018. Meta-analysis of epigenome-wide association studies of cognitive abilities. Molecular Psychiatry 23:2133-2144.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Wright, Michelle L, Taylor, Jacquelyn Y. 2018. Joint Influence of SNPs and DNA Methylation on Lipids in African Americans From Hypertensive Sibships. Biological Research For Nursing 20(2):161-167.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Kardia, Sharon R., Sung, Yun J, Winkler, Thomas W, de las Fuentes, Lisa , Bentley, Amy R, Brown, Michael R, Kraja, Aldi T, Schwander, Karen , Ntalla, Ioanna , Guo, Xiuqing , Franceschini, Nora , Lu, Yingchang , Cheng, Ching-Yu , Sim, Xueling , Vojinovic, Dina , Marten, Jonathan . 2018. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. The American Journal of Human Genetics 102(3):375-400.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Pratyaydipta, Rudra , Alaine, Broadaway K, Jhun, Min A, Bielak, Lawrence F, Wei, Zhao , Peyser, Patricia A, Epstein, Michael P, Debashis, Ghosh . 2018. Testing cross-phenotype effects of rare variants in longitudinal studies of complex traits. Genetic epidemiology 42(4):320-332.
- Jennifer Ann Smith, Erin Bakshis Ware, Jessica Danielle Faul, David R Weir, Kardia, Sharon R., Davies, Gail , Lam, Max , Harris, Sarah E, Trampush, Joey W, Luciano, Michelle , Hill, W D, Hagenaars, Saskia P, Ritchie, Stuart J, Marioni, Riccardo E, Fawns-Ritchie, Chloe , Liewald, David C. M., Okely, Judith A, Ahola-Olli, Ari , Barnes, Catriona L. K., Bertram, Lars . 2018. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications 9(1):2098.
- Erin Bakshis Ware, Jennifer Ann Smith, Liu, Jiaxuan , Turner, Stephen T, Mosley, Thomas H. 2018. DNA methylation in the APOE genomic region is associated with cognitive function in African Americans. BMC Medical Genomics 11(1):43.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Kardia, Sharon R., Feitosa, Mary F, Kraja, Aldi T, Chasman, Daniel I, Sung, Yun J, Winkler, Thomas W, Ntalla, Ioanna , Guo, Xiuqing , Franceschini, Nora , Cheng, Ching-Yu , Sim, Xueling , Vojinovic, Dina , Marten, Jonathan , Musani, Solomon K, Li, Changwei , Bentley, Amy R. 2018. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLOS ONE 13(6):e0198166.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Ward-Caviness, Cavin K, Huffman, Jennifer E, Everett, Karl , Germain, Marine , van Dongen, Jenny , Hill, W David, Jhun, Min A, Brody, Jennifer A, Ghanbari, Mohsen , Du, Lei , Roetker, Nicholas S, de Vries, Paul S, Waldenberger, Melanie , Gieger, Christian , Wolf, Petra , Prokisch, Holger , Koenig, Wolfgang . 2018. DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis. Blood 132(17):1842-1850.
- Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Evans, Mary Anne, Kardia, Sharon R., Joshi, P K, Pirastu, N , Kentistou, K A, Fischer, K , Hofer, E , Schraut, K E, Clark, D W, Nutile, T , Barnes, C L. K., Timmers, P R. H. J., Shen, X , Gandin, I , McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F , Boutin, T S, Abdellaoui, A , Zhao, W , Medina-Gomez, C , Bartz, T M, Trompet, S , Lange, L A, Raffield, L , van der Spek, A , Galesloot, T E, Proitsi, P , Yanek, L R, Bielak, L F, Payton, A , Murgia, F , Concas, M P, Biino, G , Tajuddin, S M, Seppala, I , Amin, N , Boerwinkle, E , Borglum, A D, Campbell, A , Demerath, E W, Demuth, I , Ford, I , Gialluisi, A , Gogele, M , Graff, M , Hingorani, A , Hottenga, J J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylha, M , Kuh, D , Ligthart, L , Lill, C M, Lindenberger, U , Lumley, T , Magi, R , Marques-Vidal, P , Medland, S E, Milani, L , Nagy, R , Ollier, W E. R., Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F , Ruggiero, D , Saba, Y , Schmidt, R , Schmidt, H , Slagboom, P E, Smith, B H, Sotoodehnia, N , Steinhagen-Thiessen, E , van Rooij, F J. A., Verbeek, A L, Vermeulen, S H, Vollenweider, P , Wang, Y , Werge, T , Whitfield, J B, Zonderman, A B, Lehtimaki, T , Pirastu, M , Fuchsberger, C , Bertram, L , Pendleton, N , Ciullo, M , Becker, D M, Wong, A , Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L , Uitterlinden, A G, Franceschini, N , North, K E, Metspalu, A , Boomsma, D I, Hayward, C , Chasman, D , Martin, N G, Sattar, N , Campbell, H , Esko, T , Kutalik, Z , Wilson, J F. 2017. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature communications 8(1):910.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Perinpam, Majuran , Turner, Stephen T, Lieske, John C. 2017. Association of urinary citrate excretion, pH, and net gastrointestinal alkali absorption with diet, diuretic use, and blood glucose concentration. Physiological Reports 5(19)
- Jessica Danielle Faul, Jennifer Ann Smith, David R Weir, Rannikm‰e, Kristiina , Sivakumaran, Vhinoth , Miller, Henry , Malik, Rainer . 2017. COL4A2 is associated with lacunar ischemic stroke and deep ICH. Neurology 89(17):1829-1839.
- Erin Bakshis Ware, Jessica Danielle Faul, Jennifer Ann Smith, Kardia, Sharon R., He, Zihuai . 2017. Interaction between Social/Psychosocial Factors and Genetic Variants on Body Mass Index: A Gene-Environment Interaction Analysis in a Longitudinal Setting. International Journal of Environmental Research and Public Health 14(10):1153.
- Jennifer Ann Smith, Kardia, Sharon R., Richard, Melissa A, Huan, Tianxiao , Ligthart, Symen , Gondalia, Rahul , Jhun, Min A, Brody, Jennifer A, Irvin, Marguerite R, Marioni, Riccardo , Shen, Jincheng , Tsai, Pei-Chien , Montasser, May E, Jia, Yucheng , Syme, Catriona , Salfati, Elias L, Boerwinkle, Eric , Guan, Weihua , Mosley Jr., Thomas H, Bressler, Jan . 2017. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. The American Journal of Human Genetics 101(6):888-902.
- Jennifer Ann Smith, Jessica Danielle Faul, David R Weir, Diez Roux, Ana V., Needham, Belinda L., ..., et al.. 2017. Gene-by-Psychosocial Factor Interactions Influence Diastolic Blood Pressure in European and African Ancestry Populations: Meta-Analysis of Four Cohort Studies. International Journal of Environmental Research and Public Health 14(12):1596.
- Jennifer Ann Smith, Kardia, Sharon R., Do, Anh N, Srinivasasainagendra, Vinodh , Aslibekyan, Stella , Tiwari, Hemant K, Limdi, Nita , Shah, Sanjiv J, Zhi, Degui , Broeckel, Uli , Gu, C C, Rao, D C, Schwander, Karen , Arnett, Donna K, Irvin, Marguerite R. 2017. Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies. Journal of hypertension and management 3(1):025.
- Ching-Ti Liu, Sridharan Raghavan, Nisa Maruthur, Edmond Kato Kabagambe, Jaeyoung Hong, Maggie C. Y. Ng, Marie-France Hivert, Yingchang Lu, Ping An, Amy R. Bentley, Anne M. Drolet, Kyle J. Gaulton, Xiuqing Guo, Loren L. Armstrong, Marguerite R. Irvin, Man Li, Leonard Lipovich, Denis V. Rybin, Kent D. Taylor, Charles Agyemang, Nicholette D. Palmer, Brian E. Cade, Wei-Min Chen, Marco Dauriz, Joseph A. C. Delaney, Todd L. Edwards, Daniel S. Evans, Michele K. Evans, Leslie A. Lange, Aaron Leong, Jingmin Liu, Yongmei Liu, Uma Nayak, Sanjay R. Patel, Bianca C. Porneala, Laura Rasmussen-Torvik, Marieke B. Snijder, Sarah C. Stallings, Toshiko Tanaka, Lisa R. Yanek, Wei Zhao, Diane M. Becker, Lawrence F. Bielak, Mary L. Biggs, Erwin P. Bottinger, Donald W. Bowden, Guanjie Chen, Adolfo Correa, David J. Couper, Dana C. Crawford, Mary Cushman, John D. Eicher, Myriam Fornage, Nora Franceschini, Yi-Ping Fu, Mark O. Goodarzi, Omri Gottesman, Kazuo Hara, Tamara B. Harris, Richard A. Jensen, Andrew D. Johnson, Min A. Jhun, Andrew J. Karter, Margaux F. Keller, Abel N. Kho, Jorge R. Kizer, Ronald M. Krauss, Carl D. Langefeld, Xiaohui Li, Jingling Liang, Simin Liu, William L. Lowe, Thomas H. Mosley, Kari E. North, Jennifer A. Pacheco, Patricia A. Peyser, Alan L. Patrick, Kenneth M. Rice, Elizabeth Selvin, Mario Sims, Jennifer Ann Smith, Salman M. Tajuddin, Dhananjay Vaidya, Mary P. Wren, Jie Yao, Xiaofeng Zhu, Julie T. Ziegler, Joseph M. Zmuda, Alan B. Zonderman, Aeilko H. Zwinderman, Adebowale Adeyemo, Eric Boerwinkle, Luigi Ferrucci, M. G. Hayes, Sharon L. R. Kardia, Iva Miljkovic, James S. Pankow, Charles N. Rotimi, Michele M. Sale, Lynne E. Wagenknecht, Donna K. Arnett, Yii-Der Ida Chen, Michael A. Nalls, Michael A. Province, W. H. L. Kao, David S. Siscovick, Bruce M. Psaty, James G. Wilson, Ruth J. F. Loos, Josée Dupuis, Stephen S. Rich, Jose C. Florez, Jerome I. Rotter, Andrew P. Morris, James B. Meigs. 2016. Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. The American Journal of Human Genetics 99(1):56-75.
- Erin Bakshis Ware, Jennifer Ann Smith, Kardia, Sharon R., Riehle, E , Zhao, W , Turner, Sarah E, Lieske, J C. 2015. SLC2A9 Genotype Is Associated with SLC2A9 Gene Expression and Urinary Uric Acid Concentration. Plos One 10(7)
- Youhong Liu, Jennifer Ann Smith, Liang, Jersey, ..., et al.. 2015. Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension. American Journal of Human Genetics 96(1):21-36. PMCID: PMC4289691.
- Chen,Jowei, Jennifer Ann Smith, Kardia, Sharon R., Ko, Y , Mukherjee, B , Park, S , Allison, M , Vokonas, P , Diez-Roux, A . 2014. Testing departure from additivity in Tukey's model using shrinkage: application to a longitudinal setting. Statistics in Medicine 33(29):5177-5191. PMCID: PMC4227925.
- Jennifer Ann Smith. 2013. Genetics of coronary artery calcification among African Americans, a meta-analysis. BMC Medical Genetics 14:75. PMCID: PMC3733595.
- Jennifer Ann Smith, Kardia, Sharon R., Turner, Sarah E, Sun, Y , Smith, A , Conneely, K , Chang, Q , Li, W , Lazarus, A , Almli, L , Binder, E , Klengel, T , Cross, D , Ressler, K . 2013. Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. Human Genetics 132(9):1027-1037. PMCID: PMC3744600.
- Jennifer Ann Smith, Kardia, Sharon R., Sun, Y , Lazarus, A , Chuang, Y , Zhao, W , Turner, Sarah E. 2013. Gene-Specific DNA Methylation Association with Serum Levels of C-Reactive Protein in African Americans. PLOS ONE 8(8) PMCID: PMC3747126.